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排序方式: 共有1767条查询结果,搜索用时 258 毫秒
1.
HOCK LEONG EE MBBS MRCP CHEE LEOK GOH MBBS FRCP KHOO ES-Y. CHAN PHD POR ANG MBBS MRCP 《Dermatologic surgery》2006,32(1):34-40
BACKGROUND: Acquired bilateral nevus of Ota-like macules (Hori's nevus) is a common dyschromatosis among Asian women. Q-switched lasers have been used successfully as a treatment modality. OBJECTIVE: The purpose of this study was to compare the efficacy of using the Q-switched 532 nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser followed by the 1,064 nm laser versus the Q-switched 1,064 nm Nd:YAG laser alone in the treatment of Hori's nevus. METHODS: This is a prospective left-right comparative study. Ten women with bilateral Hori's nevus were recruited and treated with a combination of the Q-switched 532 and 1,064 nm Nd:YAG lasers on the right cheek and the Q-switched 1,064 nm Nd:YAG laser alone on the left cheek. Only one laser treatment session was performed. The degree of pigmentation was objectively recorded with a mexameter. Subjective assessment was made by both patients and two blinded, nontreating dermatologists. RESULTS: At 6 months, there was a statistically significant difference (p = .009) of 35.10 points using objective mexameter measurements between the two sides, favoring the side treated with a combination of 532 and 1,064 nm laser treatment. Subjective grading by the patients and blinded dermatologists also confirmed that combination therapy was more successful after one treatment. Although combination treatment had a higher incidence of mild postinflammatory changes, this disappeared within 2 months. CONCLUSIONS: Concurrent use of the Q-switched 532 nm Nd:YAG laser in combination with the 1,064 nm laser is more effective in pigment clearance than the Q-switched 1,064 nm Nd:YAG laser alone for Hori's nevi. 相似文献
2.
目的 探讨创伤性、迟发性颅内血肿的早期诊断和治疗的临床效果。方法 对22例病人的发病年龄、性别、伤因、早期诊断和治疗效果进行了回顾性分析。经过2—6个月,按GOS评定治疗效果。结果 良好者12例,中残者5例,重残者1例,植物生存者1例,死亡者3例,死亡率为14%。结论 早期诊断和治疗本病对于提高治愈率和降低死亡率至关重要,早期手术治疗本病,乃是多数病人首选的治疗方法。 相似文献
3.
Abstract Several methods have been used to predict successful weaning and extubation among chronic obstructive pulmonary disease (COPD) patients. The objective of this study is to determine whether carbon dioxide recruitment threshold (PCO2 RT) can be used as adjunct to conventional weaning parameters to predict early weaning and successful extubation. Twelve COPD patients who were ready to be extubated based on conventional weaning parameters were divided into group A ( n = 7) and group B ( n = 5). Group A were those patients with better weaning parameters and hence a higher probability of successful extubation as compared to group B. Carbon dioxide apnoeic threshold (PCO2 AT) was obtained by hyperventilating the patient using an increment of two breaths per min until apnoea occurs. At this point, the PCO2 AT or the PaCO2 during said apnoeic period was recorded. A dead space of 150 cc is then added to the circuit until the patient starts to breathe as evidenced by the sensitivity trigger indicator. The PCO2 obtained at this period is termed PCO2 RT. After weaning for 30 min on a T-tube, another arterial blood gas is determined and this is called the PCO2 SB or the CO2 level after 30 min on spontaneous breathing. If the PCO2 SB-PCO2 RT difference is high with a sensitivity of 85.71% and specificity of 100% vs sensitivity of 57.14% and specificity of 60% using the conventional weaning parameters. Thus an increase in PCO2 SB at 30 min T-tube is indicative of impending respiratory pump failure and that other causes of failure to wean must be investigated. 相似文献
4.
Good regulation of acupuncture in simple obesity patients with stomach-intestine excessive heat type 下载免费PDF全文
In order to investigate the regulatory effect of acupuncture on obesity patients with the Stomach-Intestine Excessive Heat Type, the pre-acupunctureal and post-acupunctural obesity index and biochemical indices of 718 simple obesity patients with Stomach-Intestine Excessive Heat Type were observed. It was showed that the marked weight loss effect was achieved in the cases by acupuncture, and the biochemical indices improved. It suggests that acupuncture had a optimal regulatory effect on the function of nerve, endocrine, digestion and energy metabolism. 相似文献
5.
(胡国栋)(李小明)(黄志程)(胡道予)TheSignificanceofAnatomicalVariationsofHepaticArteryandMultipleArterialSuppliesinEmbolizationofLiverTumors¥HU... 相似文献
6.
SLE小鼠高IgG血症Fcgr2b基因序列分析 总被引:1,自引:0,他引:1
目的: 测定系统性红斑狼疮(SLE)小鼠模型-NZB/WF1双亲NZB,NZW小鼠 Fcgr2b基因启动子区核酸序列,明确Fcgr2b基因启动子区的突变性质.方法:扩增NZB,NZW小鼠Fcgr2b基因启动子DNA进行核酸序列分析.采用ELISA法测定、比较(NZB×NZW )F1×NZW回交小鼠Fcgr2b基因B/W型与W/W型组间血清总IgG 水平.结果:NZB小鼠Fcgr2b基因启动子区与正常鼠Balb/C相比存在2个部位碱基缺失,分别为13 bp及3 bp.NZW小鼠除有3个碱基置换外,与Balb/C鼠该基因启动子区序列相同.回交小鼠Fcgr2b基因B/W型组血清总 IgG水平明显高于W/W型组(P<0.0001).结论:NZB小鼠Fcgr2b基因启动子区存在碱基缺失,且该缺失突变可能与血清总IgG水平升高有关. 相似文献
7.
物理疗法治疗慢性疲劳综合征的临床观察 总被引:1,自引:0,他引:1
目的:观察与评价两种物理疗法对慢性疲劳综合征的临床疗效。方法:应用随机数字表,随机分为治疗组和对照组。治疗组36例,男12例,女24例;年龄27~65岁,平均50.80岁。对照组36例,男19例,女17例;年龄23~60岁,平均41.37岁。治疗组采用温热理疗床治疗6周。对照组采用腹部推拿手法治疗6周。观察并对比两组治疗前后记忆力或注意力下降,咽痛,颈部僵直或腋下淋巴结肿大、触痛,肌肉疼痛,多发性关节疼痛,反复头痛,睡眠紊乱,劳累后肌痛等症状体征的变化。结果:两组治疗后症状体征积分变化均有统计学意义(P<0.05);两组间疗效变化有统计学意义(P<0.05),对照组优于治疗组。结论:物理疗法对慢性疲劳综合征引起的一系列临床症状及体征具有一定程度的改善效果。 相似文献
8.
分次灌注海水致兔呼吸窘迫综合征模型的建立 总被引:4,自引:1,他引:3
目的通过向兔气管插管内灌入海水,建立海水淹溺致急性呼吸窘迫综合征模型。方法14只新西兰大白兔被随机平分为C组(对照组,无任何处理)和S组(海水组,用海水灌注)。观察分次适量海水灌入气管插管后症状学、血气分析、血液动力学、血清中肿瘤坏死因子(TNF—α)和白细胞介素-6(IL-6)的变化。2h后给每组试验兔拍摄肺CT片,并观察其组织病理学变化。结果与C组相比,S组的O2和CO2指数显著降低(P〈0.01),呼吸动力学和血液动力学的情况明显恶化。TNF—α和IL-6增高,这一结果提示肺损伤发生于兔被海水灌注之后。另外,还发现模型兔有明显的肺水肿、肺泡隔断裂和炎性渗出。结论成功复制了既符合海水淹溺的实际情况,又符合国内外急性呼吸窘迫综合征诊断标准的海水淹溺致急性肺损伤动物模型。 相似文献
9.
目的:探讨在体外c-myc反义核酸是否可通过阻断人脑胶质瘤细胞中c-myc基因的表达而抑制细胞增殖并诱导分化.方法:人工合成与c-mycmRNA起始码及其后四个密码子互补的寡聚脱氧核苷酸(简称反义核酸)片段,用它处理培养的BT325细胞,观察它对细胞增殖的影响.同时用免疫细胞化学方法检测细胞中Myc蛋白的水平以及能反映胶质瘤细胞分化的S-100和GFAP两种蛋白的水平,分析这些指标的变化.结果:发现4umol/L的c-myc反义核酸明显抑制BT325细胞的增殖和Myc蛋白的合成,且后者发生在加入反义核酸后1h,并持续24h以上,而细胞增殖受抑制要到第5日才明显.从第2日到第5日细胞中S-100和GFAP染色明显加深,反映细胞有分化趋势.用同样长度的无关序列寡聚脱氧核苷酸作对照,则未见上述变化,表明c-myc反义核酸的作用是序列特异性的.结论:c-myc反义核酸可特异地抑制BT325细胞中Myc蛋白的合成和细胞增殖,并能诱导其分化. 相似文献
10.
本文对生物软组织力学本构关系的研究进展进行了综述,内容涉及肌肉、韧带、肌腱、皮肤、粘膜、血管、腔体器官(如眼球)等领域. 相似文献